KEY RESOURCES

Evaluating the Evidence and Sample Cases

• Duke Introduction to EBM
• JAMAEvidence
• BMJ Clinical Evidence 
• User’s Guide to the Medical Literature
• Cochrane Glossary of EBM Terms
• JAMA EBM Calculators
• GetTheDiagnosis: Test Characteristics and LR Calculator
• JAMA Rational Physical Exam (Test characteristics for Exam)
• The NNT 

Guidelines National Guidelines

• Clearinghouse
• ACP Clinical Practice Guidelines
• American College of Radiology
• US preventive services task force (USPSTF)
• The Cochrane Collaboration
• High Value Care, Safety and Quality Agency for Healthcare Research Quality(AHRQ)
• BMJ Too Much Medicine
• Choosing Wisely

APPENDIX

• Levels of Evidence
• IA: Evidence from meta-analysis of randomized controlled trials
• IB: Evidence from at least one randomized controlled trial
• IIA: Evidence from at least one controlled study without randomization
• IIB: Evidence from at least one other type of quasi-experimental study
• III: Evidence from non-experimental descriptive studies, e.g. comparative, correlation, case-control studies
• IV: Evidence from expert committee or opinions or clinical experience of respected authorities or both
• Grades of Recommendations:
• A: Directly based on Level I evidence
• B: Directly based on Level II evidence or extrapolated recommendations from Level I evidence
• C: Directly based on Level III evidence or extrapolated recommendations from Level I or II evidence
• D: Directly based on Level IV evidence or extrapolated recommendations from Level I, II, or III evidence